Chemokines Chemokine Receptors & Disease

Part of the "Current Topics in Membranes" series, this work discusses the biology of chemokines and their binding partners, chemokine receptors, in normal and disease-related states. It also provides an overview of the history, molecular biology, cell biology, pharmacology, physiology, and pathophysiology of chemokines and their receptors.

Introduction: Overview and History of Chemokines and Their Receptors. The Biology CXC Chemokines and Their Receptors. The Molecular and Cellular Biology of CC Chemokines and Their Receptors. The Molecular and Cellular Biology of C and CX3C Chemokines and Their Receptors. Chemokines and Their Receptors in Hematopoietic Cell Development and Function. Chemokines in Immune Surveillance of the Intestine. Chemokines and Central Nervous System Physiology. Chemokines and Chemokine Receptors in Pulmonary Disease. Chemokines, Chemokine Receptors and Atherosclerosis. CXC Chemokines in Cancer. Chemokines and Chemokine Receptors in Infectious Disease. New Therapies Targeting Chemokine Receptors: Can Changing the Way Cells Traffic be Used to Treat Human Disease?