Molecular Medicines for Cancer: Concepts and Applications of Nanotechnology gives an account of molecular therapeutics in cancer relating to advancements of nanotechnology. It provides a description of the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology.
Section I: Nanotechnology-Based Approaches to Target Cancer
1. Nanomedicines for Cancer
[Jiasheng Tu, Birendra Chaurasiya, and Yanan Li]
2. Effect of Nanocarrier Size/Surface on Molecular Targeting in Cancer
[Eupa Ray, Ankur Sharma, Kalpesh Vaghasiya, and Rahul Kumar Verma]
3. Nanocarrier Systems for Anticancer Drug Delivery at the Subcellular Level
[Reza Mahjub and Shyh-Dar Li]
4. Chemo-Resistance Reversal Using Nanomedicines
[Can Sarisozen, Jiayi Pan, and Vladimir P. Torchilin]
5. Multifunctional Dendrimers as Cancer Nanomedicines: Peptide-Based Targeting
[Chie Kojima]
6. Targeting the Tumor Microenvironment
[Andrew Cannon, Suprit Gupta, Rakesh Bhatia, Christopher Thompson, Brad Hall, Surinder K. Batra, and Sushil Kumar]
7. Novel Nanoparticulate Drug Delivery Systems for Active Ingredients of Traditional Chinese Medicine in Cancer Therapy
[Meiwan Chen and Zhaopei Guo]
Section II: Imaging Technologies in Cancer
8. Noninvasive Imaging in Clinical Oncology: A Testimony of Current Modalities and a Glimpse into the Future
[Aniketh Bishnu, Abhilash Deo, Ajit Dhadve, Bhushan Thakur, Souvik Mukherjee, and Pritha Ray]
9. Multifunctional Nanocarriers as Theranostic Systems for Targeting Cancer
[Gaurav Pandey, Rashmi Chaudhari, Vinod Kumar Gupta, and Abhijeet Joshi]
10. Emerging Nanotechnologies for Cancer Immunodiagnosis and Cancer Immunotherapies
[Amy M. Wen, Nicole F. Steinmetz, and Sourabh Shukla]
Section III: Oligonucleotides and Gene-Based Therapies
11. Nucleic Acid Nanotherapeutics
[Siddharth Jhunjhunwala]
12. Long Non-Coding RNA and Cancer
[Mateja M. Jelen and Damjan Glavac]
13. miRNA Therapeutics to Target Multiple Molecular Pathways: Current Status, Challenges, and Future Prospects
[Lihui Zhu and Guofeng Cheng]
14. Alliance of Lipids with siRNA: Opportunities and Challenges for RNAi Therapy
[Anu Puri, Mathias Viard, Paul Zakrevsky, Lorena Parlea, Krishna Pal Singh, and Bruce A. Shapiro]
15. Lipid Nanocarriers for RNAi-Based Cancer Therapy
[Ranganayaki Muralidharan, Anish Babu, Narsireddy Amreddy, Janani Panneerselvam, Meghna Mehta, Anupama Munshi, and Rajagopal Ramesh]
16. Advancements in Polymeric Systems for Nucleic Acid Delivery
[Vinayak Sadashiv Mharugde, Sudeep Pukale, Saurabh Sharma, Anupama Mittal, and Deepak Chitkara]
17. Self-Assembling Programmable RNA Nanoparticles: From Design and Characterization to Use as an siRNA Delivery Platform
[Brandon Roark, Morgan Chandler, Faye Walker, Lucia Milanova, Viktor Viglasky, Martin Panigaj, and Kirill A. Afonin]
18. DNA Repair and Epigenetics in Cancer
[Loredana Zocchi and Claudia A. Benavente]
19. Genomic Engineering Utilizing the CRISPR/Cas System and Its Application in Cancer
[Amit Kumar Chaudhary, Rajan Sharma Bhattarai, Chalet Tan, Channabasavaiah B. Gurumurthy, and Ram I. Mahato]