Medical Physiology

Medical Physiology: Principles for Clinical Medicine richly presents the physiology knowledge necessary for clinical practice. Along with the latest information on how the human body reacts to internal and external changes, the text provides a deep understanding of how physiologic systems coordinate to maintain optimal health. Emphasizing normal physiology, discussions of pathophysiology are also included to show how altered functions are involved in disease processes. This fifth edition focuses on the physiologic principles key to understanding human function, and places them clearly in their fundamental context in clinical medicine. Clinical Focus essays highlight how and where physiology relates to clinical medicine and diagnosis. New Integrated Medical Sciences essays highlight the connections between physiology and other basic sciences, such as pharmacology, biochemistry, and genetics. Extensive chapter revisions in the Neuromuscular, Gastrointestinal, Renal, and Blood and Immunology parts have been provided by new expert contributors. End-of-chapter USMLE-style review questions, with answers and explanations, as well as new Clinical Application exercises , help students master the material. Conceptual diagrams facilitate comprehension of difficult concepts and presents both normal and abnormal clinical conditions. Active Learning Objectives, Chapter Summaries, and full-color artwork and tables facilitate learning and study. A companion website offers additional resources for students including animations, additional review questions, additional clinical application exercises, advanced clinical problem-solving exercises, and suggested readings.

Preface Contributors PART I CELLULAR PHYSIOLOGY Chapter 1 Medical Physiology: An Overview Chapter 2 Cell Signaling, Membrane Transport, and Membrane Potential PART II NEUROMUSCULAR PHYSIOLOGY Chapter 3 Action Potential, Synaptic Transmission, and Nerve Function Chapter 4 Sensory Physiology Chapter 5 Motor System Chapter 6 Autonomic Nervous System Chapter 7 Integrative Functions of the Central Nervous System Chapter 8 Skeletal and Smooth Muscle PART III BLOOD AND IMMUNOLOGY Chapter 9 Blood Composition and Function Chapter 10 Immunology, Organ Interaction, and Homeostasis PART IV CARDIOVASCULAR PHYSIOLOGY Chapter 11 Overview of the Cardiovascular System and Hemodynamics Chapter 12 Electrical Activity of the Heart Chapter 13 Cardiac Muscle Mechanics and the Cardiac Pump Chapter 14 The Systemic Circulation Chapter 15 Microcirculation and Lymphatic System Chapter 16 Special Circulations Chapter 17 Control Mechanisms in Cardiovascular Function PART V RESPIRATORY PHYSIOLOGY Chapter 18 Ventilation and the Mechanics of Breathing Chapter 19 Gas Transfer and Transport Chapter 20 Pulmonary Circulation and Ventilation/Perfusion Chapter 21 Control of Ventilation PART VI RENAL PHYSIOLOGY AND BODY FLUIDS Chapter 22 Kidney Function Chapter 23 Regulation of Fluid and Electrolyte Balance Chapter 24 Acid-Base Homeostasis PART VII GASTROINTESTINAL PHYSIOLOGY Chapter 25 Gastrointestinal System Functions Chapter 26 Liver Functions and Immune Surveillance Chapter 27 Motility and Gastrointestinal Regulation PART VIII TEMPERATURE REGULATION AND EXERCISE PHYSIOLOGY Chapter 28 Regulation of Body Temperature Chapter 29 Exercise Physiology PART IX ENDOCRINE PHYSIOLOGY Chapter 30 Endocrine Control Mechanisms Chapter 31 Hypothalamus and the Pituitary Gland Chapter 32 Thyroid Gland Chapter 33 Adrenal Gland Chapter 34 Endocrine Pancreas Chapter 35 Endocrine Regulation of Calcium, Phosphate, and Bone Homeostasis PART X REPRODUCTIVE PHYSIOLOGY Chapter 36 Male Reproductive System Chapter 37 Female Reproductive System Chapter 38 Fertilization, Pregnancy, and Fetal Development Appendix A: Common Abbreviations in Physiology Appendix B: Normal Blood, Plasma, or Serum Values Glossary Index