A number of genes have been identified that are associated with an increased Body Mass Index (BMI), the standard measurement of obesity. This title provides a forum for discussion of discoveries, approaches, and ideas. It includes reference guide for researchers involved in molecular biology and related fields.
Covers different techniques for the cryopreservation of gametes and embryos, production of transgenic and null (knockout) animals (use of ES cells), generation of conditional/inducible mutant animals, use of gene-trap mutagenesis, analysis of allele-specific expression, use of new reporter constructs, humanizing of transgenic animals, and more.
Discusses various aspects of immunohistochemistry and in situ hybridization technologies and the role they play in reaching a cancer diagnosis. This work provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, and the benefits and limitations of each method.
Presents advances and comprehensive reviews in cell biology both plant and animal. This title contains articles which include Mechanisms of Gradient Detection: A Comparison of Axon Pathfinding with Eukaryotic Cell Migration; Leptin and the Regulation of Hypothalamic-Pituitary-Adrenal Axis; and Focal Adhesion and p53 Signaling in Cancer Cells.
Presents advances and comprehensive reviews in cell biology both plant and animal. This volume includes articles such as: Function and Evolution of the Vacuolar Compartment in Green Algae and Land Plants (Viridiplantae); and, Cell biology and pathophysiology of diacylglycerol kinase family - morphological aspects in tissues and organs.
International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Praise for the Series: "Invaluable reading for all biologists." --NATURE "In keeping with the high standards set by the editors...carefully prepared and edited in the customary fine format and well-illustrated style of Academic Press publications...this series is a significant contribution to a science that impinges on many fields." --THE
Covers the developments in computer technology. This title addresses such topics as: hardware, software, web technology, communications, theoretical underpinnings of computing, and novel applications of computers. It includes surveys and tutorials on various computer technologies.
Intends to aid students who wish to gain an understanding of solving biological issues with computer programs. This manual provides an exploration of model development, model validation, and model refinement, enabling students to experience advancements made in biology by mathematical models.
Features articles that focus on ecosystem structure, ecological processes, and the forcing of these systems by external stresses, principally climate and fisheries related. This title references related articles on marine ecological processes to facilitate research. It includes an introductory overview of marine ecological processes.
This third edition of Mathematica by Example is completely compatible with recent Mathematica versions. Highly readable and informative, this volume is geared toward the beginning Mathematica user, and focuses on the most often used features of this powerful tool. The book covers popular applications of mathematics within different areas including calculus, linear algebra, ordinary differential equations, and partial differential equations. The book does an excellent job of providing information that beginning Mathematica users need, I think the use of Mathematica is excellent. The Mathematica graphical output is excellent
--William Emerson, Metropolitan State College
Colin Mathers who leads the Global Burden of Disease group in WHO has confirmed that, in the 2004 GBD, 13.1% of global Daily Adjusted Life Years are attributable to mental or neurological disorders. While the proportions vary very widely from about 10% in low income countries to over 25% in high income countries, it is clear that there is a need for understanding how to address this issue.
This volume aims to provide a comprehensive overview of the public health principles of mental and neurological disorders. This vast range of health conditions affects people across the life course, from developmental disabilities in childhood, to schizophrenia and substance abuse in adults, and dementia in old age. Despite this diversity, they all share many features: they are
Covers chemical biology, ubiquitin derivatives and ubiquitin-like proteins, deubiquitinating enzymes, proteomics as well as techniques to monitor protein degradation. This work includes chapters that focus on application of techniques. It covers topics such as: E1 Enzymes, E2 Enzymes, E3 Enzymes, Proteasomes, and Isopeptidases.
Presents the various developments in microsystems and devices for biochemical processes. This title informs the reader on the research findings using original reviews. It reviews and analyzes developments in the field.
Presents the principles and disease examples relevant to molecular neurology. This book describes the molecular aspects of neurological disorders. It provides an introduction to neurological disorders for basic scientists. It is useful for those studying the molecular basis of neurology, or developing therapies in neurology.
Pregnancy is a unique period in life associated with significant hormonal and other physiologic changes in female patients, which may trigger or alter the course of neurological and psychiatric disorders. This book reviews the findings in this field, giving the neurologist and non-neurologist information they need to determine the best treatment.
This book presents the 24 discoveries in infectious diseases that have merited Nobel Prize recognition since the inception of the awards in 1901. Grouped according to biological groups rather than chronology, each discovery includes a biographical sketch of the laureate(s), a description of the research, and a summary of the current status of the field. In addition, consideration is given to the relevance of the research on the general field of biology and medicine. "Rifkind and Freeman's account serves as an introduction for the general reader to microbiology, immunology and infectious diseases...There are also some interesting points for the specialist."
- Robin A. Weiss, University College London for NATURE MEDICINE (June 2006)
"...unique features are the
The contributions in this volume emphasize analysis of experimental data and analytical biochemistry, with examples taken from biochemistry. They serve to inform biomedical researchers of the modern data analysis methods that have developed concomitantly with computer hardware.
The rate of introduction of new pharmaceutical products has increased rapidly over the past decade, and details learned about a particular drug become obsolete as it is replaced by newer agents. Principles of Clinical Pharmacology focuses on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. The coverage of these principles in this book will be of particular benefit to individuals engaged either in the teaching or study of sound therapeutic technique or in the investigation of pharmacological agents. "...this book fulfills the long-felt need for an updated publication in Clinical Pharmacology."-INDIAN JOURNAL OF PHARMACOLOGY (2003)
"...this book is for the reader who wants a detailed in- depth understanding of clinical
Presents comprehensive reviews of drug substances, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This title profiles creatine monohydrate and fexofenadine hydrochloride, as well as five others. It meets the information needs of the drug development community.
A compendium that provides assessment of critical issues related to erythroid biology. It integrates developmental, epigenetic, methodological, biochemical, and clinical aspects to provide an overview of their interrelationships and importance to the generation of the red cell. It offers a discussion of red cells.
Presents informative summaries of the progress in a variety of subject areas within inorganic chemistry, ranging from bio-inorganic to solid state studies. This title features comprehensive reviews on the developments in the field. Suitable for advanced researchers, it includes contributions from some of the leading experts in the field.
The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics research. This title includes important reviews of the interest to geneticists and their colleagues in affiliated disciplines, providing researchers an overview and synthesis of the findings in the area.
