Cell surface small molecules and macromolecules, such as members of cholesterol family (including steroid hormones), the glycolipid family (sphingolipids), the glycoprotein family (both N-linked and O-linked), and a vast array of other receptors have been shown to be involved in normal and abnormal cellular processes. The 11th International Symposium on Cell Surface Macromolecules, held in Mohali, India, in February 2017 provided a comprehensive update on the major advances in this area. Presenting selected contributions from this meeting, this book comprises 24 chapters, which provide in-depth analyses of data on the role of cell surface macromolecules in cellular function and their alterations associated with pathological conditions. It includes comprehensive
This book focuses on biodiesel combustion, including biodiesel performance, emissions and control. It brings together a range of international research in combustion studies in order to offer a comprehensive resource for researchers, students and academics alike. The book begins with an introduction to biodiesel combustion, followed by a discussion of NOx formation routes. It then addresses biodiesel production processes and oil feedstocks in detail, discusses the physiochemical properties of biodiesel, and explores the benefits and drawbacks of these properties. Factors influencing the formation of emissions, including NOx emissions, are also dealt with thoroughly. Lastly, the book discusses the mechanisms of pollution and different approaches used to reduce
This book comprehensively introduces fundamentals and applications of fermentative hydrogen production from organic wastes, consisting of eight chapters, covering the microbiology, biochemistry and enzymology of hydrogen production, the enrichment of hydrogen-producing microorganisms, the pretreatment of various organic wastes for hydrogen production, the influence of different physicochemical factors on hydrogen production, the kinetic models and simulation of biological process of fermentative hydrogen production, the optimization of biological hydrogen production process and the fermentative hydrogen production from sewage sludge. The book summarizes the most recent advances that have been made in this field and discusses bottlenecks of further development. This
This book summarizes recent advances in the processing of waste biomass resources to produce biofuels and biochemicals. Worldwide interest in clean energy sources, environmental protection, and mitigating global warming is rapidly gaining momentum and spurring on the search for alternative energy sources, especially for the transportation and industrial sectors. This book reviews the opportunities presented by low-cost organic waste materials, discussing their suitability for alternative fuel and fine chemical production, physicochemical characterization, conversion technologies, feedstock and fuel chemistry, refining technologies, fuel upgrading, residue management, and the circular economy. In addition, it explores applied aspects of biomass conversion by
This book analyses the state of the natural environment and the causes of its degradation using the biosphere approach. Further, those issues that must be resolved immediately on the global level are identified following the ideas defined by V.I. Vernadsky, and new principles of Man-Nature interaction are pursued. The modern world currently faces three global trends inducing biosphere degradation and the aggravation of ecological hazards, namely: a) rapid and uncontrolled growth of human population on the Earth and insufficient natural resources to sustain it; (b) technogenesis development; and (c) global climate change and the aggravation of natural disasters. Ecological safety and military security are becoming the crucial conditions for the survival of modern
This book provides a comprehensive review of biosynthetic approaches to the production of industrially important chemicals and the environmental challenges involved. Its 19 chapters discuss different aspects of biosynthetic technology from the perspective of leading experts in the field. It covers various biorefinery approaches, including the use of microbes, metabolically engineered plants, biomass-based and green technology methods. Further, it examines important research in the areas of organic and hazardous waste composting, management and recovery of nutraceuticals from agro-industrial waste, biosynthesis and technological advancements of biosurfactants and waste water bioremediation. This book contributes to the scientific literature on biosynthetic technologies
This book presents a comprehensive collection of various in situ and ex-situ soil remediation regimes that employ natural or genetically modified microbes, plants, and animals for the biodegradation of toxic compounds or hazardous waste into simpler non-toxic products. These techniques are demonstrated to be functionally effective in connection with physical, chemical, and biological strategies. Soil and water contamination through heavy metals, hydrocarbons and radioactive wastes is of global concern, as these factors have cumulative effects on the environment and human health through food-chain contamination. The book discusses the utilization of algae, plants, plant-associated bacteria, fungi (endophytic or rhizospheric) and certain lower animals for the sustainable
Rather than an exhaustive review of all the pathologic conditions of the female breast, Breast Cancer and its Precursor Lesions focuses on the current knowledge, understanding and issues related to breast cancer and its benign lesions that are associated with an increased risk for the subsequent development of cancer. This book targets the language, diagnostic terms and critical communication that must take place between primary care physicians, breast surgeons, oncologists, and general surgical pathologists interested in the pathologist's perspective on these important diseases. The volume also reviews the current terminology and how to read or write meaningful pathology reports on these entities, the foils and nuances of the pathology and implications for management,
This book offers a valuable guide for practicing bridge engineers and graduate students in structural engineering; its main purpose is to present the latest concepts in bridge engineering in fairly easy-to-follow terms.The book provides details of easy-to-use computer programs for:· Analysing slab-on-girder bridges for live load distribution.· Analysing slab and other solid bridge components for live load distribution.· Analysing and designing concrete deck slab overhangs of girder bridges under vehicular loads.· Determining the failure loads of concrete deck slabs of girder bridges under concentrated wheel loads.In addition, the book includes extensive chapters dealing with the design of wood bridges and soil-steel bridges. Further, a unique chapter on structural
Author:Emilie Masson
Marion Berbineau
Émilie Masson
Publishing date:2018
This book focuses on the needs of railway operators in terms of wireless communications, divided in two main categories: the commercial services and the operational needs. Then, all available technologies that can be used to provide Internet access on board trains and all the other operational applications requiring high capacity are detailed. Finally, challenges and trends in railway telecommunications are highlighted, through the presentation of the future and emerging technologies, the current discussions and works in the different authorities, and the key challenges and scientific barriers.
This book deals with the design and construction of buildings for nanoscale science and engineering research. The information provided in this book is useful for designing and constructing buildings for such advanced technologies as nanotechnology, nanoelectronics and biotechnology. The book outlines the technology challenges unique to each of the building environmental challenges outlined below and provides best practices and examples of engineering approaches to address them:- Establishing and maintaining critical environments: temperature, humidity, and pressure- Structural vibration isolation- Airborne vibration isolation (acoustic noise)- Isolation of mechanical equipment-generated vibration/acoustic noise- Cost-effective power conditioning- Grounding facilities
The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science. Thus the scope of coverage includes a broad range of topics of pure and applied organometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience. The individual volumes of Topics in Organometallic Chemistry are thematic. Review articles are generally invited by the volume editors. All chapters from Topics in
This volume brings together a plethora of protocols and experimental methods used by scientists to study calpains, their inhibitors, and their substrates. It also explores bioinformatic approaches to calpain substrate identification. The chapters in this book are divided into five parts and cover topics such as production and purification of calpains; determination of calpain localization, expression, and activity; identification of calpain-activated protein function; interrogation of calpastatin; and manipulation of calpain expression. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory
Author:Andreas OEchsner
Andreas Öchsner
Ardiyansyah Syahrom
Mohd Al-Fatihhi bin Mohd Szali Januddi
Muhamad Noor Harun
Publishing date:2018
This book provides comprehensive mechanobiological insights into bone, including the microstructure of cancellous bone and its realistic loading in the human body. This approach considers different types of loads, i.e. static and dynamic, and the response under uniaxial and multiaxial loading conditions. The book also reviews additional factors influencing biomechanical properties, e.g. fluid transport. In closing, the mechanobiological approach is discussed in the context of the finite element method.
This excellent new book summarizes the whole range of systemic cancer therapies, explaining their mode of action and potential side-effects, as well as their clinical applications. It is divided into three sections. The first tackles the theoretical basis of cancer chemotherapy: following an historical introduction, the different treatment modalities are explained in the context of basic tumor biology. The text then moves on to the subject's practical aspects and covers dosing and drug delivery together with an extensive discussion of possible side-effects. Finally, Priestman looks at chemotherapy in the management of cancers. The book has a consistency of style which makes a wealth of complex information both readily accessible and easily understandable.
Cancer Genetics is a collection of chapters covering the key recent developments in cancer genetics which have an impact on clinical care. The target audience will be physicians and scientists who need to be apprised on the most recent developments in the field.
Cancer Grading Manual addresses all histopathologic aspects of tumor pathology essential for grading of tumors. It discusses the history and basic tenets of tumor grading; principles of microscopic grading of tumors; ancillary methods currently used to improve tumor grading; and new techniques used in evaluating tumors and formulating prognosis. It is designed to be a practice-oriented, concise and well-illustrated resource for diagnostic surgical pathologists and pathology residents.The manual is organized by specific organ systems. Each chapter begins with an introduction and describes in detail the optimal and most widely used system for grading common tumors.
This book discusses the methods synthesizing various carbon materials, like graphite, carbon blacks, carbon fibers, carbon nanotubes, and graphene. It also details different functionalization and modification processes used to improve the properties of these materials and composites. From a geometrical-structural point of view, it examines different properties of the composites, such as mechanical, electrical, dielectric, thermal, rheological, morphological, spectroscopic, electronic, optical, and toxic, and describes the effects of carbon types and their geometrical structure on the properties and applications of composites.
This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in the past decade, including numerous color figures. The individual chapters are based on the respective authors' studies and experiences, providing tips from the frontline to help researchers overcome bottlenecks in their own work. It highlights a number of cutting-edge techniques, such as 3D cell culture, microfluidic droplet technique, and microfluidic chip-mass spectrometry interfaces, offering a first-hand impression of
The articles in this volume provide a comprehensive overview of our current understanding of the roles played by cellular factors in the early steps of retroviral replication. A better understanding of these functions will provide critical new insights into retrovirus-host cell interactions and is likely to prove useful for the future development of effective antiretroviral therapies.
Polymericmaterials, both inert anddegradable,constantlyinteractwiththe surroundings. Because of this interaction changes take place in the polymer matrix and small molecules are released to the environment. Reliable me- ods for testing biodegradability and environmental interaction of renewable resources and biodegradable polymers are required to answer the rema- ing questions concerning the environmental impact of these future materials. Inthecaseofdegradablepolymersmultiplefactorsaffectthedegradation process and small changes in the chemical structure or product formulation may change the susceptibility to degradation or cause different degradation product patterns, rendering the product less environmentally adaptable. - velopment of sustainable polymeric materials
This book serves as a self-contained reference source for engineers, materials scientists, and physicists with an interest in relaxation phenomena. It is made accessible to students and those new to the field by the inclusion of both elementary and advanced math techniques, as well as chapter opening summaries that cover relevant background information and enhance the book's pedagogical value. These summaries cover a wide gamut from elementary to advanced topics.The book is divided into three parts. The opening part, on mathematics, presents the core techniques and approaches. Parts II and III then apply the mathematics to electrical relaxation and structural relaxation, respectively. Part II discusses relaxation of polarization at both constant electric field
Millionsof people are already affected by weather-related shocks every year in WestAfrica and climate change is highly likely to increase these threats. In thewake of climate change, rising temperatures, increasingly irregular rainfalland more frequent natural hazards will endanger the ways of life of vulnerablepopulation groups in this region and destabilize their human security. A surgein violence and conflicts could take place. One of the conflict constellationscould be between farmers and herders. These groups are highly vulnerable toclimate change due to their dependence on natural resources Millions of people are already affected by weather-related shocks every year in West Africa and climate change is highly likely to increase these threats. In the wake of
Clinical Hepatology Principles and Practice of Hepatobiliary Diseases provides clear and comprehensive coverage of the etiology, mechanisms of disease, diagnosis, and practical management of the entire spectrum of liver and biliary disorders. It also affords an excellent, evidence-based review of the rapidly expanding field of hepatobiliary diseases.
