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Data wydania

2000 rok - 2020 rok

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2 dni - 30 dni

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    • Jest 116 produktów.

    SGA-Mangelgeburt

    SGA-Mangelgeburt

    Autor: Urs Eiholzer
    Data wydania: 2016
    Dieses Buch erörtert leicht verständlich Herkunft, Entstehungsweise, Verlaufsform und mögliche Auswirkungen von SGA (Small for Gestational Age) einschliesslich der Behandlungsmöglichkeiten. Die neusten Forschungsergebnisse belegen eindrücklich, dass es bei SGA-Kindern als Folge einer zeitweisen Unterversorgung mit Nährstoffen über epigenetische Prozesse schon im Mutterbauch zu einer Umprogrammierung des Stoffwechsels kommt. Der Fetus reagiert auf den Mangel, bremst das Wachstum und reduziert Muskel- und Fettmasse. Zudem passt er die Regulation von Insulin und Nebennierenrindenhormonen an. Ohne Therapie haben SGA-Kinder später ein erhöhtes Risiko, eine zu kleine Körpergrösse zu haben oder an Adipositas, einem Typ-2-Diabetes oder an hohem Blutdruck zu erkranken. Bei
    175,00 zł
    Skin Barrier Function

    Skin Barrier Function

    Autor: T. Agner
    Data wydania: 2016
    Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration
    747,00 zł
    Sleep-Related Breathing...

    Sleep-Related Breathing Disorders

    Autor: H. C. Lin
    Data wydania: 2017
    Many sleep-related breathing disorders (SRBD), especially obstructive sleep apnea, originate from upper airway abnormalities. The connection to cardio- and cerebrovascular comorbidities is significant and the impact on the general health of patients is noteworthy. In recent years, important advances have been made in the research, diagnosis, and treatment of SRBD due to a multidisciplinary approach. This volume incorporates contributions in which the efforts and expertise of more than thirty outstanding experts are shared. It provides a concise, practical, and comprehensive review of sleep medicine and will enable researchers and physicians to stay updated on the latest developments.
    652,00 zł
    Stimulation of the...

    Stimulation of the Peripheral Nervous System

    Data wydania: 2015
    Among neuromodulation procedures, electrical stimulation of peripheral nerves (PNS) is probably the most underappreciated modality. Although PNS is used for all kinds of medical conditions, ranging from chronic neuropathic pain and headache to epilepsy, depression, hypertension and heart failure, its importance is frequently overshadowed by spinal cord stimulation and deep brain stimulation. While the earlier version of this book dealt exclusively with various pain syndromes, this new volume covers the entire spectrum of PNS applications. Written by recognized authorities in their respective fields, the chapters of this title describe the use of PNS in the management of neurological, psychiatric, otorhinolaryngological, cardiovascular, pulmonary, colorectal and
    825,00 zł
    Streptococcal Pharyngitis

    Streptococcal Pharyngitis

    Autor: B Mahy
    H Zeichhardt
    Data wydania: 2003
    Group A streptococcal pharyngitis is one of the most common, but also controversial infections clinicians are faced with every day. Clinical diagnosis is often not specific; laboratory data can be misleading and are frequently misinterpreted. Despite the in vitro effectiveness of penicillin, it does not always eradicate the organism from the upper respiratory tract. Numerous newly introduced antibiotics are expensive or not even available in many countries. In this book, internationally acknowledged experts deal in detail with the complexity of streptococcal pharyngitis and the remaining controversies. It offers an overview of the virulence factors of Streptococcus pyogenes, the pathogenesis of pediatric and adult streptococcal pharyngitis, and the epidemiology of
    593,00 zł
    Successes and Limitations...

    Successes and Limitations of Targeted Cancer Therapy

    Data wydania: 2014
    The treatment of patients with advanced malignancies has undergone remarkable change in the last few years. While in the past decisions about systemic therapy were largely based on the performance status of a patient, oncologists today also take into account the pathological and molecular characteristics of the patient's tumor. Targeting specific molecular pathways important for tumorigenesis has become the preferred way of treatment for many types of malignancies. With these advances come new challenges including the optimization of therapy, recognizing and dealing with side effects and, importantly, the development of resistance. This book provides an up-to-date overview of the advances and limitations of targeted therapy for several tumor entities including breast
    679,00 zł
    Surgery for the Dry Eye

    Surgery for the Dry Eye

    Autor: G Geerling
    Data wydania: 2008
    All adnexal structures - the tear system, the lids and the orbit as well as neuronal and cellular components of the ocular surface itself, i.e. the cornea and conjunctiva - are involved in tear production and maintenance. If any part of this complex functional unit mutates either primary or secondary to disease, changes in tear film and ocular surface known as dry eye may occur. In this volume a panel of well-established international experts provides the theoretical foundation and describes the interaction of the ocular adnexa and surface in dry eye. Current guidelines for the diagnosis and medical management are also given. The main focus lies on surgical concepts exceeding techniques such as to block the lacrimal drainage system or lid surgery, but encompasses
    845,25 zł
    Syphilis & Co.

    Syphilis & Co.

    Autor: Peter Weisenseel
    Data wydania: 2018
    Sexuell übertragbare Erkrankungen wie Syphilis und Co. treten seit einigen Jahren wieder deutlich häufiger auf. Ein gesundes Wissen zu diesem Thema gehört zum Führerschein des Lebens und ist der beste Schutz vor unangenehmen Überraschungen. Oder hätten Sie gewusst, vor welchen Erkrankungen auch Kondome nicht zuverlässig schützen? Anhand von Anekdoten und Beispielen aus vielen Sprechstunden gibt Dr. med. Peter Weisenseel Einblick in den Umgang mit sexuell übertragbaren Erkrankungen und deren Randgebieten: ohne moralischen Imperativ, dafür feinfühlig und mit charmantem Humor - damit das hängenbleibt, was soll, und das, was es zu vermeiden gilt, gar nicht erst haften bleibt. Für ein gutes Gefühl am Morgen danach.
    71,00 zł
    Telomeres and Telomerase

    Telomeres and Telomerase

    Autor: P Slijepcevic
    Data wydania: 2009
    Telomeres are essential functional elements of eukaryotic chromosomes. Their fundamental biological role as protectors of chromosome stability was identified for the first time in the 1930s by Hermann Muller and Barbara McClintock based on pioneering cytological experiments. Modern molecular research carried out more recently revealed that telomeres and telomerase play important roles in processes such as carcinogenesis and cellular senescence. This special issue presents the most recent developments in this highly active field of research. It is becoming increasingly clear that molecular pathways involved in regulation of telomere length and structure are functionally linked with pathways involved in DNA damage response, cellular stress response, chromatin
    309,75 zł
    The Arboranan Frogs

    The Arboranan Frogs

    Data wydania: 2018
    This monograph is a comprehensive study of arboranan frogs (families Hylidae, Phyllomedusidae, and Pelodryadidae). It presents results achieved over a 38-year period. As arboranan frogs are practically cosmopolitan, absent only from sub-Saharan Africa and southeastern Asia, this publication is an international venture with collaborators from Australia, Brazil, Canada, Ecuador, Germany, Thailand, and the USA. Introductory chapters cover phylogeny, classification, biogeography, life history, and population declines of Arboranae, but the focus of the book is on oogenesis, spermatogenesis, early embryogenesis, and, especially, the structure and evolution of chromosomes. Like its predecessors on terraranan and hemiphractid frogs (2010 and 2012, respectively), this volume
    714,00 zł
    The Diabetic Foot Syndrome

    The Diabetic Foot Syndrome

    Autor: A. Piaggesi
    Data wydania: 2017
    In recent years, "diabetic foot" has become the common name given to chronic complications of diabetes mellitus in the lower limb. This book provides an up-to-date picture of the clinical scenario, the latest understanding of the mechanisms in regard to pathology, the current standards of therapy, and the organizational tasks that a modern approach to such a complex pathology warrants. All contributors have delivered articles that are as informative and straight-to-the point as possible, including not only their own experience in the field, but also giving a wider picture to link each article to the other. The Diabetic Foot Syndrome is not only relevant to specialists, but also to all the caregivers involved in the management of the patients at risk for developing the
    726,00 zł
    The Hippocampus in Clinical...

    The Hippocampus in Clinical Neuroscience

    Data wydania: 2014
    The hippocampus is one of the most intriguing structures of the human brain. Damage to this part causes symptoms ranging from transient disorders accompanied by tiny lesions to severely debilitating cognitive disorders with marked tissue loss. This publication provides a predominantly clinical approach to the complex workings of the hippocampus from different perspectives, ranging from basic principles to specific diseases. The first part of the book summarizes current knowledge regarding the structure and physiology of the hippocampus and establishes the ties to basic neuroscience. The second part deals with the function and assessment of the human hippocampus, including memory function, neuropsychological measures, and conventional and functional imaging studies. The
    742,00 zł
    The Impact of Nutrition and...

    The Impact of Nutrition and Diet on Oral Health

    Data wydania: 2020
    Most oral diseases are preventable, yet they remain the most globally common noncommunicable disorders, affecting people throughout their lifetime. Lifestyle, including diet and food choice, is central to the occurrence of oral disease. Nutrition and diet can impact the development and status of the oral cavity as well as the progression of illness. Also, poor oral health can influence the ability to eat and, consequently, to maintain an adequate diet and nutrient balance. This book, consisting of 14 chapters, provides current information on the impact of nutrients (macro- and micro-elements and vitamins) and diet on oral health and vice versa (i.e., the impact of oral health on diet/nutrition). It also reviews possible oral health effects of probiotics as well
    676,00 zł
    Transition of Care

    Transition of Care

    Data wydania: 2018
    Pediatricians face many questions and challenges during patients' transition from childhood to adulthood. Chronic diseases justify long-term medical, psychological, educational, and social management. The establishment of networks with adult endocrinologists is, therefore, very important to achieving optimal conditions for a successful transition period. In this book, leading experts discuss major public health issues such as diabetes and obesity. They also review genetic diseases, including Turner syndrome and congenital adrenal hyperplasia. All clinical cases are presented in a focused way to highlight any issues which might be discussed by the doctor with patients and family. Psychological approaches are debated as are proposals for defining specific tools to
    551,00 zł
    Tuberculosis and War

    Tuberculosis and War

    Data wydania: 2018
    Tuberculosis (TB) remains the largest cause of adult deaths from any single infectious disease, and ranks among the top 10 causes of death worldwide. When TB and war occur simultaneously, the inevitable consequences are disease, human misery, suffering, and heightened mortality. TB is, therefore, one of the most frequent and deadly diseases to complicate the special circumstances of warfare. Written by internationally acclaimed experts, this book provides a comprehensive analysis of the status of TB before, during and after WWII in the 25 belligerent countries that were chiefly involved. It summarizes the history of TB up to the present day. A special chapter on "Nazi Medicine, Tuberculosis and Genocide" examines the horrendous, inhuman Nazi ideology, which during
    569,00 zł
    Tumors in Adolescents and...

    Tumors in Adolescents and Young Adults

    Autor: D. P. Stark
    Data wydania: 2016
    The field of adolescents and young adult (AYA) oncology is experiencing a very challenging time. This book is a guide to the key issues for any clinician and health professional managing AYA with cancer in Europe. Emphasis is on collaboration between adult and pediatric specialists. Authors present their perception of the current state of the most prominent primary issues in AYA oncology. Chapters cover cross-cutting issues such as disease epidemiology, systems of care, access to innovative therapy and late effects of treatment and survivorship for AYA-onset cancers. There are discussions of the latest developments and the most important cancer types for AYA, including the shared perspectives of adult and pediatric specialists. Throughout the book recurrent
    821,00 zł
    Uric Acid in Chronic Kidney...

    Uric Acid in Chronic Kidney Disease

    Data wydania: 2018
    Hyperuricemia is often associated with life-style related disorders such as diabetes mellitus, hypertension, and dyslipidemia, which, in turn, are major causes of CKD. Improved management of hyperuricemia is thus expected to be beneficial for both the general population and CKD patients. This book presents new information on uric acid in tubular transport, early recognition of renal lesions, genetic predisposition, preeclampsia, metabolic syndrome, diabetes, high blood pressure in the young, and the relationship with vitamin D. Moreover, the relationship between AKI and uric acid, as well as the rejection of renal transplants due to hyperuricemia, are discussed. This publication will be of interest to both general practitioners and researchers working in the field of
    558,00 zł
    Using and Understanding...

    Using and Understanding Medical Statistics

    Autor: D.E. Matthews
    D. E. Matthews
    V.T. Farewell
    V. T. Farewell
    Data wydania: 2015
    The fifth revised edition of this highly successful book presents the most extensive enhancement since Using and Understanding Medical Statistics was first published 30 years ago. Without question, the single greatest change has been the inclusion of source code, together with selected output, for the award-winning, open-source, statistical package known as R. This innovation has enabled the authors to de-emphasize formulae and calculations, and let software do all of the 'heavy lifting'. This edition also introduces readers to several graphical statistical tools, such as Q-Q plots to check normality, residual plots for multiple regression models, funnel plots to detect publication bias in a meta-analysis and Bland-Altman plots for assessing agreement in clinical
    210,00 zł
    Vestibular Disorders

    Vestibular Disorders

    Data wydania: 2019
    This collection of articles on the latest developments is written by experts in various sub-disciplines - medical and paramedical - of vestibular disorders. Contributions discuss various manifestations of vestibular disorders and how to diagnose and treat them. The different areas are put into context to support the clinician in the diagnosis and treatment of patients with dizziness, imbalance, and vertigo. New diagnostic tools are presented as are new approaches to the understanding of clinical signs and underlying pathologies. Otolaryngologists seeking to provide up-to-date assessment and care will find this publication a valuable and indispensable read. The contributions presented appeal not only to otolaryngologists of all levels of experience, but also to
    677,00 zł
    Vitamin D in Clinical Medicine

    Vitamin D in Clinical Medicine

    Data wydania: 2018
    Vitamin D deficiency is prevalent today not only among the elderly but pervasively throughout all ages of life.This is due, in part, to systemic diseases that affect vitamin D metabolism, to changes in lifestyle, such as insufficient exposure to sunlight, and to increased use of sunscreen. Apart from the obvious effects of vitamin D deficiency on skeletal metabolism, the problem is assuming even greater significance because observational and interventional studies have linked vitamin D deficiency to cardiovascular disease, cancer, and diabetes. This book addresses a variety of important issues that have emerged from this fast-moving area of clinical medicine. The topics include assays of vitamin D and its binding protein, effects on aging and associated
    621,00 zł