Pediatric Endocrinology

Also known as hypercortisolism, Cushing's syndrome is a hormonal disorder caused by prolonged exposure of the body's tissues to high levels of the hormone cortisol. This uncommon disease requires considerable expertise for optimum management. This issue covers the full spectrum of this disease, including basic principles, features of Cushing's syndrome, and diagnosis and treatment.

1. Screening and Diagnosis of Cushing's Syndrome (Findling and Raff) 2. History of Cushing's Syndrome and Harvey Cushing (Aron) 3. The Hypothalamic-Pituitary-Adrenal Axis (Including POMC and Feedback) (Jacobson) 4. Glucocorticoid Action, GR/MR, 11BOHSD, Steroidogenesis (Stewart) 5. Glucocorticoid Sensitivity/Resistance Syndromes (Malchoff) 6. The Metabolic Syndrome and Cardiovascular Risk in Cushing's Syndrome (Colao, Pivonello and Faggiano) 7. Osteoporosis in Cushing's Syndrome (Shaker) 8. Differential Diagnosis and Imaging in Cushing's Syndrome (Nieman) 9. Subclinical Cushing's Syndrome in Adrenal Incidentalomas (Terzolo) 10. Macronodular Adrenal Cushing's Syndrome - Carney Complex - - I Bourdeau and A (Lacroix and Bourdeau) 11. Cognitive Function and Cerebral Assessment in Patients with Cushing's Syndrome (Neuropsychology) (Lacroix, Bourdeau, Bard, Boulanger and Cohen) 12. Pituitary Surgery and Post-Operative Management (Biller, Swearingen and Utz) 13. Pituitary Radiotherapy (Vance) 14. Laparoscopic Adrenalectomy (Young) 15. Exogenous Cushing's Syndrome and Glucocorticoid Withdrawal (Including Oral, Parenteral, Inhaled, Nasal, Dermal) (Leinung)